There are several locations from the books and films that you can travel to in the game by passing through portals created by Portkeys.
List of Portkey Locations
This Circus was at its height in 1927. It was featured as a Portkey Location during the Brilliant Event: Circus Calamitous Part II.
The home of Rubeus Hagrid. This place is featured in the game as both a page in the Registry as well as a Foundable, and a location you can go to via a Portkey.
The best place for Witches and Wizards to purchase their wand.
The Train all students take to travel Hogwarts School of Witchcraft and Wizardry. This Location was featured during the Brilliant Event: Back to Hogwarts.
This Shop is not only an Inn, it was also featured as a Portkey Location during the Brilliant Event: Lost Love Part I.